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(S,S,S)-AHPC hydrochloride 是 von Hippel-Lindau (VHL) 氨基砌块。(S,S,S)-AHPC (Compound 27) 常作为 (S,R,S)-AHPC 的阴性对照。(S,R,S)-AHPC 是基于 VH032 的 VHL 配体,可用于募集 VHL 蛋白。
(S,S,S)-AHPC hydrochloride 是 von Hippel-Lindau (VHL) 氨基砌块。(S,S,S)-AHPC (Compound 27) 常作为 (S,R,S)-AHPC 的阴性对照。(S,R,S)-AHPC 是基于 VH032 的 VHL 配体,可用于募集 VHL 蛋白。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 112 | 现货 | |
5 mg | ¥ 248 | 现货 | |
10 mg | ¥ 397 | 现货 | |
25 mg | ¥ 653 | 现货 | |
50 mg | ¥ 990 | 现货 | |
100 mg | ¥ 1,590 | 现货 | |
200 mg | ¥ 2,370 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 298 | 现货 |
产品描述 | (S,S,S)-AHPC hydrochloride is a von Hippel-Lindau (VHL) aminoblock. (S,S,S)-AHPC (Compound 27) is often used as a negative control for (S,R,S)-AHPC. (S,R,S)-AHPC is a VHL ligand based on VH032 and can be used to recruit VHL proteins. |
体外活性 | VHL is one of the most popular E3 ligases being recruited by bifunctional Proteolysis-targeting chimeras (PROTACs) to induce ubiquitination and subsequent proteasomal degradation of a target protein. |
别名 | (S,S,S)-VH032-NH2 hydrochloride, (S,S,S)-AHPC盐酸盐 |
分子量 | 467.02 |
分子式 | C22H31ClN4O3S |
CAS No. | 2115897-23-7 |
Smiles | Cl.Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@H](O)CN2C(=O)[C@@H](N)C(C)(C)C)cc1 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | H2O: 99 mg/mL (211.98 mM), Sonication is recommended. DMSO: 60 mg/mL (128.47 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
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